Does my promising new compound have the potential to be a drug?
Does my promising new compound have the potential to be a drug? It’s the question at the heart of every drug discovery project. In our latest blog post, we explore how we can help project teams to approach this question from a DMPK perspective.
A Brief History of Pharmacokinetics
Pharmacokinetics (PK) seeks to provide a mathematical understanding of the blood concentration/time-course of an administered compound or drug. PK is part of a broader topic
Addicted to Speed: Drug Discovery’s Unhealthy Obsession with the Fastest Possible Design-Make-Test-Analyse Cycle
“The most successful drug discovery project is the one with the fewest compounds synthesised”.
DMPK Scientists and Where to Find Them…
Firstly, we would like to thank everybody who took the time to complete our recent questionnaire. We had a great response, which gives us a
It’s all in the Detail: Avoiding Misinterpretation of DMPK Screening Assay Results
Common challenges in obtaining robust and reproducible DMPK assay data.
What do you mean I don’t always need to screen in hepatocytes?!
We share how the published drug classification systems can be utilised to help design a screening cascade tailored to providing the most relevant information for your project.